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TMAO (trimethylamine N-oxide) is produced by gut bacteria from choline, lecithin, and L-carnitine-rich foods (mainly fish, meat, egg, and dairy)
IV administration should be done by medical professionals only
A significant age group sex interaction was observed, with pomegranate extract reducing plasma TMAO AUC in female participants of premenopausal age and male participants while showing opposite effects in female participants assigned to the Older (postmenopausal age) group
Fluoxetine also decreased the activity of 17-beta-hydroxysteroid dehydrogenase type 6 (17-HSD6), a steroidogenesis-related enzyme, and lowered serum testosterone levels by affecting the steroidogenic capacity of Leydig cells
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