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To view a copy of this licence, visit About this article Cite this article Majernkov, N., Marmolejo-Garza, A., Salinas, C.S

10.3390/ijms24021582 64 LouJ.-S.ZhaoL.-P.HuangZ.-H.ChenX

Alterations in the normal function of excitatory amino acid carrier 1 affect cysteine transport and GSH synthesis impairing zinc homeostasis (the thiol group of GSH can function as a principal Zn 2+ chelator for the maintenance of Zn 2+ homeostasis in neurons) and oxidative stress, enhancing susceptibility to ischemia-induced neuronal cell death in the hippocampus (162164)