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Former UK prime minister Boris Johnson wrote in the Daily Mail that he asked his doctor about taking semaglutide after he noticed some colleagues were suddenly thinner, who told him he was an "ideal candidate." "I must have been losing four or five pounds a week maybe more when all at once it started to go wrong

Importantly, tirzepatide injections are FDA-approved for Type 2 diabetes (Mounjaro) and as of late 2023 for obesity (Zepbound)

A researcher who spent eight weeks at 8mg before reducing to 4mg retains the metabolic adaptations from that period

Rotating your injection site, letting the alcohol swab dry completely before injecting, and avoiding skin thats bruised or tender can all help reduce stinging