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Similarly, women with type 2 diabetes and obesity who are not ovulating regularly may experience improved ovulatory function with significant weight loss and better glycaemic control

MetS was induced in a group of 10 animals by feeding them a high-fat diet (HFD) for 24 weeks, while a control group of 10 animals received a normalipid/regular fat diet (ND) (AIN93M) during the same period

Despite significant progress observed in clinical trial development, there remains a scarcity of published clinical data, particularly regarding long-term safety, efficacy across diverse populations, and real-world effectiveness

10.1186/s10020-023-00746-y 103 ToldoS.MezzaromaE.BuckleyL