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Your gastrointestinal system needs time to adjust to the new compound even if the mechanism is similar
Historically, the development of appetite-suppressing drugs has focused on targeting receptors or transporters of neurotransmitters and neuromodulators released by neurons involved in central feeding regulation
In June 2024, for instance, Lilly published detailed results from its Phase II SYNERGY-NASH study, demonstrating that tirzepatide could potentially improve fibrosisliver scarringin patients with metabolic dysfunction-associated steatohepatitis (MASH)
The researchers concluded that patients who tapered off semaglutide maintained a stable body weight for the first 26 weeks
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