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TL;DR: In a large sample of US Veterans, GLP-1 drugs were associated with reduced risk of substance use and psychotic disorders, seizures, neurocognitive disorders (including Alzheimers disease and dementia), coagulation disorders, cardiometabolic disorders, infectious illnesses and several respiratory conditions, but increased risk of gastrointestinal issues, hypotension (low blood pressure), and some kidney-related conditions

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Key differentiators include insurance acceptance, appointment speed, and the range of medications available

Individuals with a history of thyroid cancer (semaglutide carries a warning for medullary thyroid carcinoma)