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Their prophylactic efficacy in preventing travelers diarrhea is particularly well established (378, 379), alongside a well-defined beneficial role in managing acute diarrhea in children (380)

Insights from CREDENCE trial indicate an acute drop in estimated glomerular filtration rate during treatment with canagliflozin with implications for clinical practice

However, insurance does not cover compounded medications, so patients pay out of pocket

Supporting a dominant role for diet composition in establishing the Firmicutes : Bacteroidetes ratio, previous work has shown that mice maintained on a high-fat diet had a similar cecal Firmicutes : Bacteroidetes ratio to those maintained on a high-carbohydrate diet 77