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The dose-response data broke down as follows: 1mg dose: 8.7% average weight loss at 48 weeks 4mg dose: 15.2% average weight loss at 48 weeks 8mg dose: 21.1% average weight loss at 48 weeks 12mg dose: 24.2% average weight loss at 48 weeks Placebo: 2.1% average weight loss at 48 weeks The week-by-week progression told an equally compelling story

This range derives from scaling the effective doses in rat studies (approximately 10 micrograms per kilogram of body weight) to human physiology using established interspecies conversion factors

GLP-1 medications are FDA-approved treatments

But the biological rationale is sound, the ingredient evidence is real, and adding a clean, single-ingredient 10g hydrolyzed collagen to your daily protein intake is a discussion-worthy nutritional option for appropriate adults, subject to your licensed healthcare provider's guidance