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The prevalence of its reduced form in cells is due to the activity of glutathione reductase, which is both constitutive and inducible in response to oxidative stress
Effective for superficial skin concerns but limited systemic distribution
There are no clinically significant drug-drug interactions documented at standard doses, though theoretical interactions with strong CYP3A4 inhibitors (ketoconazole, ritonavir) or inducers (rifampin, carbamazepine) should be considered
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