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TGF-1 suppression The review confirms that GHK-Cu decreases secretion of TGF-1 by dermal fibroblasts
This is especially important for patients who have any GI-related problems: reflux/heartburn, SIBO/SIFO, chronic constipation, leaky gut, patients who are on acid blockers, etc
This causes depressurization of the NP and inward collapse of AF fibers, which causes degeneration similar to annular disc herniation
Patients who have a severe deficiency will notice the results earlier than patients with a mild deficiency
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