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showed that preventive use of N-acetylcysteine (NAC, a precursor of glutathione) over six months significantly reduces the incidence of flu and flu-like episodes, especially in high-risk elderly individuals

The researchers felt that N-acetylcysteine and glutathione could accomplish this by protecting the DNA from free radical damage

While physiological concentrations of NO are essential for various cellular functions, its overproduction, particularly from the upregulation of inducible nitric oxide synthase (iNOS), can have deleterious effects in the context of sepsis 54,55

However, most commercial product claims extrapolate from small studies, animal data, or practitioner-reported outcomes rather than large independently funded randomized trials