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This HO-CO pathway has been recently proposed to be involved in the defence against oxidative stress and the deleterious effects of NO, since it removes the cytotoxic free heme, and produces some molecules with antioxidant and anti-inflammatory effects, such as biliverdin and CO [8, 3840]
But when you add them all together, what initially looked affordable can turn into a major headache
In: Harris JR, Korolchuk VI, editors
One study found thigh bioavailability ran about 12% lower compared to the abdomen
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