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The FLOW trial also highlights the renal protective effects of GLP-1RAs, suggesting a close link between renal and cardiovascular benefits, which warrants further mechanistic studies (256)
Coll Antropol
This framework highlights that long-term metabolic stability during GLP-1RA therapy depends not only on energy balance but also on maintaining proportionality between oxidative throughput and substrate-supported regenerative capacity
Hippocampus mitochondrial MnSOD activation by a SIRT3 activator, honokiol, correlates with its deacetylation and upregulation of FoxO3a and PGC1 in a rat model of ammonia neurotoxicity
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