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Although a dual agonist capable of activating both GLP1R and GIPR , Tirzepatide preferentially activates GIPR more, over GLP1R
In trials with secondary endpoints, such as STEP 9 [38], semaglutide also resulted in significant improvements in obesity-related comorbidities, including osteoarthritis-related pain and rates of reversion to normoglycaemia, further underscoring its broad clinical utility
While extremely rare, allergic reactions to components in the IV solution can occur
Efficacy of GLP-1 Agonists vs
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