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Choline may increase cholinergic tone and could theoretically augment adverse reactions when combined with acetylcholinesterase inhibitors such as donepezil
10.1007/s00268-012-1663-4 146 VukojevicJ.SiroglavicM.KasnikK.KraljT.StancicD.KokotA.et al (2018)
As an essential vitamin that supports the health of your nerve cells and is vital for DNA synthesis and red blood cell production, B12 can be a game-changer, especially for those who do not get enough from their diet or have absorption issues
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