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The author AK declared that they were an editorial board member of Frontiers, at the time of submission

HG-PA-treated Fgf13 KD Human glomerular endothelial cells (HRGEC) and Fgf13 knockout mice and Fgf13 plus Prkn double KO mice and induced with HFD/STZ, found that Fgf13 deficiency could be important for the regulation of mitochondrial homeostasis in glomerular endothelial cell (GEC) and T2DN processes through the bifunctionality of Parkin in promoting mitophagy and inhibiting apoptosis [128]

This depletion can hinder the liver's ability to detoxify, leading to a buildup of toxins and further health complications

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