Thirty-five were preclinical (i.e., in rodents or cell culture)
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Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to 2015: a systematic analysis for the global burden of disease study
During the immune exhaustion characteristic of chronic infection, an increase in CTLA-4 expression is observed, which may increase IDO activation (234)