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It not only enhances insulin production and release, but also decreases glucagon secretion, increases glucose uptake and glycogen synthesis in peripheral tissues, delays gastric emptying, and increases satiety

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On average, GLP-1s can lead to 15% or more body weight reduction, and for those who have lived with obesity for years, their lives will change dramatically. Tran says using GLP-1s can lead to less spending on food, with users eating smaller portions, cutting unnecessary snacking, finding fast food less appealing, and experiencing reduced cravings for high-sugar foods

Most studies focused on liraglutide, whereas the newer GLP-1RAs have better appetite-suppressant and weight-reduction actions