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They were the main reason the trials titrate slowly
Impairment of short-chain fatty acid (SCFA) and l-isoleucine biosynthesis in gut microbiome persists beyond 30 days after recovery from COVID-19, which could contribute to persistent leaky gut and dysbiosis in PASC patients 237,238
The primary concerns include manufacturing consistency, dosing accuracy, product quality, sterility, and limited regulatory oversight compared with FDA-approved medications
Some donors may experience mild side effects such as lightheadedness, dizziness, or fatigue, which are generally temporary and can be mitigated by resting and rehydrating after the donation
