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Though the regulatory agency generally does accept the determinations of panels like these, it can and has rejected panel votes in the past
10.1016/j.neurobiolaging.2013.11.027 8
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We found that pharmacological MT1 and MT2 agonism failed to replicate the effects of melatonin in suppressing IL-5 production ( Figures 3B, D ) or IL-13 production ( Figures 3C, E )
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