This practice originates from concerns about physical interactions in the gut (binding, pH changes, competition for transporters) rather than systemic pharmacokinetic conflicts
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It took Beth decades to learn about it and figure it out
Compared to ethanol or aqueous extracts, methanol extract exhibited superior antibacterial activity against all tested bacterial strains (Gram positive bacteria, Gram negative bacteria, and Candida sp.), particularly against Gram positive bacteria (Staphylococcus aureus, Streptococcus pneumoniae, Bacillus cereus, and Enterococcus faecalis)