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It also inhibits the activity of CYP3A11 and CYP1A2, preventing the bioactivation of APAP to the toxic metabolite NAPQI (Piver et al., 2001

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First, NAC serves as an alternative substrate for 3-MST with a much higher catalytic efficiency than cysteine, generating N-acetylcysteine persulfide (N-AceCysSSH) and other persulfide species and thereby boosting the cells antioxidant capacity

Weinberg, F