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Significance during GLP-1 therapy: Hypocalcemia (low calcium levels) can result in muscle spasms or seizures
Pharmaceutical companies are developing triple agonists that add glucagon agonism to GLP-1 and GIP
In trials with semaglutide was added on to insulin with or without metformin, severe hypoglycemia was reported in 1% of patients receiving the 14 mg tablets, 1% of patients receiving placebo, and 0% of the patients receiving the 7 mg tablets
Finding the right balance requires ongoing check-ins with your doctor to manage side effects, costs, and your long-term results
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