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They advocate for a treatment approach that is: Symptom-led : Recognising that many patients become symptomatic well before their next scheduled dose, meaning they are being under-treated
Cloning, expression, characteristics and application of novel bifunctional glutathione synthetase
2.4 Genotyping of selected genetic variants Genetic variants were primarily genotyped using real-time-qPCR using TaqMan commercial probes in a Stratagene Mx3000p Real-Time PCR System and AriaMx Real-Time PCR System (Agilent Technologies, Santa Clara, CA, USA) ( Supplementary Table 2 )
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