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This has clinical significance because, in general, the volume of a stroke correlates with severity and the resultant degree of disability of the patient [7, 8]

While IV therapy is highly effective, it is invasive, costly, and impractical for the daily, long-term management required by complex chronic illnesses like Long COVID and ME/CFS

For instance, treating 20 type 2 diabetics with 35 mg PLP along with 3 mg activated folate and 2 mg vitamin B12 improved skin sensation in diabetic peripheral neuropathy (Walker 2010)

The key takeaway is that under normal usedrawing from an aluminum-covered vial into a transparent syringe and injecting within a minute or sothere is nothing to worry about