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rBMAT adipocytes in the proximal tibia had an intermediate phenotype, with a limited decrease in lipid by osmium staining after 1 day (16%, P = 0.470), 82% loss after 3 days at high-dose leptin ( P 80% suppression of the G0s2 : Pnpla2 ratio in cBMAT-filled CV that was driven by cachexia-induced decreases in G0s2 that exceeded changes in Pnpla2 (Fig

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