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Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice
In db/db mice and HG-exposed HK-2 cells, overexpression of mitofusin 2 restores mitochondrial function, suppresses mitochondrial oxidative phosphorylation, reduces tubular apoptosis and eventually alleviates diabetic kidney injury, and the reverse tendency is observed in mitofusin 2 short hairpin RNA treated db/db mice (82)
There are so many that are said to work, but the success rate varies
In a study conducted via Lu et al
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