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The medication is absorbed through the subcutaneous tissue, so proper placement affects both comfort and effectiveness

25,26 Effects on Epicardial Adipose Tissue GLP1-RAs decrease the volume of epicardial adipose tissue, which is often elevated in HFpEF and is a source of proinflammatory cytokines and adipokines

1 About the SELECT trial and SCORE real-world study SELECT was a randomized, double-blind, parallel-group, placebo-controlled trial designed to evaluate the efficacy of Wegovy (semaglutide) 2.4 mg versus placebo as an adjunct to standard of care for the prevention of MACE in people with overweight or obesity and established CVD with no prior history of diabetes

It commands this strong grade because it turns a boring health routine into an enjoyable, sour-sweet confectionery experience that is completely guilt-free