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Residual gastric contents (RGC) Although the overwhelming majority of articles assessed have accepted that GLP-1 RAs can significantly increase residual gastric contents by delaying gastric emptying time as scientific fact, not all have retained this belief

One study enrolled older adult inpatients with depression without an explicitly stated diagnostic framework

doi:10.1136/gut.26.1.26

Increases in both proinflammatory cytokines and oxidative and nitrosative stress by activation of microglia via TLR3 could lead to increased IDO activity in microglia, resulting in reduced tryptophan levels, increased kynurenine catabolites, and decreased 5-HT and melatonin synthesis