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In human colorectal cancer (CRC), miR-873 is downregulated and this increases ELK1 expression [92] as described above for miR-130b

The WT or mutant plasmids were then transfected into HNF4-negative SNU449 cells together with the control pRL-TK (Renilla Luciferase, Promega), and the control pcDNA3 vector or pcDNA3-HNF4 construct

The findings, presented at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting and published simultaneously in JCO Oncology Practice, suggest those taking GLP-1 medications had approximately 30% lower odds of developing breast cancer compared with non-users

Cardiovascular disease risk factors, type 2 diabetes mellitus, and the Framingham Heart Study