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The 2026 Clinical Obesity review found GLP-1 users running 2630% lower ferritin than comparison groups, and a separate analysis of 18,746 adults with type 2 diabetes found GLP-1 users had a 54% higher likelihood of lower ferritin than users of a different diabetes drug class

These cytokines also contribute to IR through mechanisms including inhibitory phosphorylation of insulin receptor substrate-1 (IRS-1) and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-B) pathway, while also promoting glucocorticoid resistance and HPA axis hyperactivity [80]

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Those with dull skin / sunburnt