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Dose selection in the research literature varies with the application: musculoskeletal-injury studies commonly report 200250 g twice daily near the affected site, while gastrointestinal-focused protocols use 250500 g once or twice daily, subcutaneously

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The solution was transferred at room temperature into a 3 L round bottom flask, diluted with 260 mL of methanol and 760 mL of water, treated rapidly under vigorous stirring with 15 mL of a freshly prepared aqueous solution of sodium borohydride (0.145 g, 3.83 mmol) that causes the formation of a dark brown colloidal suspension