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The four compounds engage non-overlapping mechanisms Epithalon through telomerase activation and pineal-axis bioregulation, MOTS-c through AMPK and mitochondrial biogenesis, NAD+ through co-factor restoration, and 5-Amino-1MQ through NNMT enzyme inhibition
Baseline HbA1c in these studies varied from 8.1 to 8.5% (6569 mmol/mol)
Psychiatry 26 , 43944408 (2021)
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