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Conclusion While treatment of adults with CKD and T2D should be holistic, SGLT2is should be prioritised as foundational therapy, independent of BMI, to reduce cardiorenal risk
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Current Evidence and Clinical Trial Findings Phase 2 data published in the NEJM (2023) showed dose-dependent body weight reductions with retatrutide over 48 weeks, with gastrointestinal side effects being the most commonly reported
Mercury can come in three main forms: Elemental Inorganic Organic Organic mercury is the most toxic form and more readily crosses the blood brain barrier
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