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Ideal candidates are those with one or more of the following: Type 2 diabetes or prediabetes, especially when lifestyle changes and other medications have been insufficient Obesity or substantial weight gain (BMI 30 kg/m, or 27 kg/m with comorbidities) Elevated cardiovascular risk (e.g., hypertension, dyslipidemia, or heart disease) Before initiating therapy, clinicians should conduct a comprehensive assessment that includes a detailed medical history, cardiovascular risk profile, weight history, and review of previous attempts at lifestyle and pharmacologic interventions
The assessment of fertility in women is more complex than in men, and there is a lack of direct biomarkers
In healthy people, these large, undigested fragments of gluten protein are eventually harmlessly excreted and do not provoke an immune response (Fasano 2009)
They both increase endogenous insulin (signaling) that will make the liver more GH-sensitive (see Leung et al
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