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PL among those taking DPP-4i (mean absolute difference 4.6% [ p 5% for some groups, a threshold of weight loss endorsed by many obesity guidelines as having a significant impact on obesity-related morbidity and mortality
For weight management , NICE has approved specific GLP-1 receptor agonists (TA875 for semaglutide 2.4mg/Wegovy
Whilst GLP-1 receptor activation can exert multiple direct neuroprotective effects, the protective influence of GLP-1 receptor agonists may occur indirectly through the restoration of the dysfunctional insulin signaling associated with neurodegenerative disease
Longhi, editor, Managing psychosexual consequences in chronic diseases (pp
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