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Thus, we cannot conclude that the improved health of the animals correlates with increased levels of GLP-1 in vivo and will likely need to move to a larger animal model to address this question

For providers who are prescribing these medications, it is important to properly counsel patients to manage their weight loss

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Its design incorporates a fatty diacid moiety via a linker at lysine-26 to enable albumin binding and extend the half-life to approximately five days, supporting once-weekly administration in clinical study protocols