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Gene expression was also reduced in Maxi, however, this was not statistically significant (Table 3 b)

Compound 2 , NADPH, and incubation time was varied as following: 1) TGR and 2 , no preincubation, 2) TGR, 2 , and NADPH, no preincubation, 3) TGR and 2 , 15 min preincubation, 4) TGR, 2 , and NADPH, 15 min preincubation, 5) TGR and NADPH followed by 15 min preincubation, 2 was added after 15 min preincubation, 6) TGR and 2 followed by 15 min preincubation, NADPH was added after 15 min preincubation

Goat anti-mouse IgG or anti-rabbit IgG (Boster, Wuhan, China) conjugated to HRP was used as the secondary antibody

however, when the burden increases, those naturally built in systems can often fail to keep up with demand