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Melanotan II is not an approved human medicine in any regulatory zone (FDA, EMA, KL)

Li J, Liu F, Wang H et al (2010) Systematic mapping and functional analysis of a family of human epididymal secretory sperm-located proteins

According to the FDA prescribing information, nausea affects approximately 15-30% of patients (dose-dependent) and is usually mild to moderate in severity, often improving after the first few weeks as tolerance develops