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Cardiovascular safety DPP-4 inhibitors provide no benefits above the standard of care for people with established or high risk of atherosclerotic cardiovascular disease, heart failure or chronic kidney disease

2 Nevertheless, it has been found that despite eight available families of hypoglycemic compounds (biguanides, sulfonylureas, glinides, -glucosidase inhibitors, DPPIV inhibitors, GLP1 analogues, thiazolidinediones, and SGLT2 inhibitors), 3.0.CO;2-W 9

Purine synthesis inhibitors Purine synthesis inhibitors are not associated with hypertension and may in fact have an antihypertensive effect