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Polonikov, 2020)

In this study, we followed the core principles of MR, using the following formula to calculate the causal relationship: where SNP-pqtl represents the effect of an SNP on cis-pQTL, while SNP-migraine indicates the effect of the same SNP on migraine risk

These include proteins, peptides, cytokines, microRNAs, and metabolites that act as endocrine signals linking contracting muscles and other organs to distant tissues

In the present study, more than a two-fold increase in expression has been demonstrated for these two proteins in riboflavin deficient cells, suggesting that steroid catabolism and androgen synthesis are possibly enhanced after riboflavin deficiency