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It is important to clean the injection site (such as the arm or thigh) with an antiseptic to avoid any risk of infection
some may respond within 15 minutes at higher doses [9] These medications work by enhancing nitric oxide-mediated relaxation of penile smooth muscle, facilitating increased blood flow during sexual stimulation
What the Data Actually Show | Evidence Level | Sermorelin Alone | GHK-Cu Alone | Sermorelin + GHK-Cu | |---|---|---|---| | Phase III RCT | Yes (pediatric GHD) | No | No | | Phase II RCT (adults) | Yes (Vittone 1997) | One skin-aging trial | No | | Animal studies | Multiple | Multiple | None identified | | In vitro mechanistic | Extensive | Extensive | None identified | | Case series / observational | Limited | Limited | Anecdotal only | The FDA-approved indication for sermorelin covers pediatric GH deficiency
The deciding question it poses is whether the theoretical benefit justifies the added cost, complexity, and interaction risk in your particular clinical picture
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