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(iii) The Icelandic Medicines Agency has submitted 150 reports of GLP-1RAs-related suicidal or self-injurious behaviors (SSIBs) to the European Medicines Agency (EMA) [14]
Lixisenatide (Adlyxin): A once-daily incretin mimetic injection for type-2 diabetes
Theoretical and Class-Level Risks These have not been confirmed in cagrilintide trials but are flagged because they appear in related amylin or GLP-1 class data: pancreatitis, gallbladder disease, severe hypoglycemia (mainly when combined with insulin or sulfonylureas), and acute kidney injury secondary to dehydration from severe nausea or vomiting
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