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Results The mean weight loss among patients prescribed GLP-1 analogue monotherapy at 12 months was 11.42 kg, SD 9.95 (9.6% TBWL)

However, even modest changes in usual glucose patterns may temporarily affect energy levels in some individuals

Despite the low incidence of serious side effects and discontinuation of treatment due to these effects reported in clinical trials, the prevalence of gallstones and obstructive jaundice linked to orlistat demands attention [42, 71]

Side Effects and Safety Profiles Shared Side Effects Both compounds share a similar gastrointestinal (GI) side-effect profile, typical of the GLP-1 class