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Serious Side Effects Less common but more serious side effects can include acute pancreatitis (severe abdominal pain that does not resolve), acute gallbladder disease (upper stomach pain, jaundice, fever), acute kidney injury (often related to dehydration from GI side effects), serious allergic reactions, hypoglycemia (especially if taking other diabetes medications), and mental health changes including suicidal thoughts
Pancreatitis is a known, rare risk with GLP-1s
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