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UV radiation triggers additional melanin distribution and darkening in the visible skin layers
10.1155/2020/3469840 61 LiX.LiW.YangP.ZhouH.ZhangW.MaL
The extraordinary potency of Dihexa was demonstrated in scopolamine-induced cognitive deficit models in rats (Benoist et al., published in the Journal of Pharmacology and Experimental Therapeutics, 2011)
ROS and oxidatively modified macromolecules function as damage-associated molecular patterns (DAMPs), engaging pattern recognition receptors (PRRs) on microglia, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), to initiate inflammatory cascades ( Microglia, the resident immune cells of the CNS, are tightly regulated under physiological conditions to maintain neural homeostasis
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