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These findings have positioned FOXO4-DRI as one of the most mechanistically specific senolytic peptides currently available for research purposes, distinguishing it from small-molecule senolytics that operate through broader cellular pathways

NMDA Receptor Modulation Mechanism MK-801 studies (MK-801 is a more selective NMDA antagonist) showed BPC-157 counteracted locomotion abnormalities, stereotyped sniffing, and ataxia