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How SLU-PP-332 Works ERR pan-activation Binds and activates all three ERR isoforms (, , ) with preferential ERR activity - orphan nuclear receptors that govern energy metabolism
These mediators not only facilitate the recruitment of inflammatory cells such as macrophages and monocytes into the myocardial tissue but also trigger myocardial inflammatory responses
In SUMMIT, tirzepatide cut the risk of heart failure outcomes by 38% compared to placebo
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