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Individuals with pre-existing liver disease, hepatitis B or C, acetaminophen-induced liver injury history, or conditions causing glutathione depletion face substantially elevated overdose risk at standard doses

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NOVO and LLY both are conducting large studies to demonstrate whether thats true for their respective drugs

8 If a patient consumes food around the same time of APAP ingestion, there may be a delay in the time of, but not the extent of, drug absorption