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However, these early changes may be modest and continue to develop over subsequent weeks
The risk of MACE was reduced by 12% (HR 0.88, 95% CI 0.840.94) with GLP-1RAs and by 11% (HR 0.89, 95% CI 0.830.96) with SGLT2is compared with that in placebo groups, suggesting that GLP-1RAs and SGLT2is reduce the risk of MACE to a similar extent
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